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 About 10 results found for searched term "Mitochondrial Related" (0.125 seconds)

Cat.No.  Name Target
M2830 Mdivi-1 Dynamin
Mitochondrial division inhibitor 1
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM.
M10756 Flavokawain A Apoptosis
CAS# 37951-13-6
Flavokawain A is an anticarcinogenic agent, a chalcone found in kava extracts with antitumor activity. Flavokawain A induces apoptosis through Bax protein-dependent and mitochondrial-dependent apoptosis pathways. Flavokawain A has the potential to be used in bladder cancer related research.
M40536 T0467 Mitochondrial Related
T0467 is a potential PINK1-Parkin signaling activator that activates mitochondrial parkin translocation in a PINK1-dependent manner, but does not induce mitochondrial aggregation of PINK1 in dopaminergic neurons. It can be used in the study of Parkinson's disease and related disorders.
M40912 Tricaprilin Others
Trioctanoin; Glyceryl trioctanoate
Tricaprilin is an orally active medium chain triglyceride that improves mitochondrial metabolism by inducing a ketosis state. It can be used in studies related to Alzheimer's disease (AD).
M40980 HU6 Mitochondrial Related
HU6 is a mitochondrial oxidative phosphorylation uncoupler that can be used in studies related to non-alcoholic steatohepatitis (NASH).
M40989 Azemiglitazone potassium PPAR
MSDC-0602K
Azemiglitazone potassium is a thiazolidinediones that binds to PPARγ with an IC50 value of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). It can be used in studies related to non-alcoholic steatohepatitis (NASH).
M42885 FGIN 1-43 Others
FGIN 1-43 is an effective and specific ligand for the mitochondrial diazepam binding inhibitor (DBI) receptor (related to the production of neurosteroids).
M45064 MTK458 Others
EP-0035985
MTK458 is an orally active, brain-permeable PINK1 activator that binds to and stabilizes the active isoform of PINK1, thereby enhancing mitophagy and promoting mitochondrial autophagy (Mitophagy). It can be used in studies related to Parkinson's disease (PD).
M45348 4-Hydroperoxy cyclophosphamide DNA Alkylator/Crosslinker
4-Hydroperoxy cyclophosphamide, the active metabolite form of the precursor Cyclophosphamide, cross-links DNA and induces T-cell apoptosis independent of caspase receptor activation, as well as activating the mitochondrial death pathway through the generation of reactive oxygen species (ROS). It can be used in studies related to rheumatoid arthritis and autoimmune diseases.
M54718 PP405 Others
PP405 is a potent localized mitochondrial pyruvate carrier (MPC) inhibitor that acts on cellular metabolic pathways to up-regulate LDH and activate stem cells to promote hair growth, and can be used in studies related to androgenetic alopecia.



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